Monocytes, granulocytes and endothelial cells (Cunha et al.,Ģ005). Necrosis factor alpha (TNF-α) are released by macrophages, Mediators (nitric oxide and prostaglandin E2), and severalĬytokines such as interleukin-1β (IL-1β), IL-6, IL-10 and tumour Inflammation is also involved as a pathogenetic mechanism in the development of many diseases, such as diabetes,Ĭardiovascular and neurodegenerative diseases and cancer Such as microbial infections, burns, allergens, mechanical injuries and other noxious stimuli (Lawrence, Willoughby, & Gilroy,Ģ002). Inflammation is a local defence reaction of body to injury Medicinal plant for the treatment of inflammation in ancient The literature data reported a wide range of biological properties, such as antibacterial against numerous pathogenicĪgents, cytotoxic, antihistamine, anti-inflammatory, and antimalarial activity. These fruits contain significant amounts of polyphenols. These, Cornelian cherries gained lately an increasing importance. Which are particularly rich in antioxidant compounds. In recent years, consumers increased their interest to fruits Pelargonidin-3-O-rutinoside (PubChem CID: 4425626) Chlorogenic acid (PubChem CID: 1794427) (+)-Catechin (PubChem CID: 9064) (−)Epicatechin (PubChem CID: 72276) Caffeic acid (PubChem CID: 689043) Ellagic acid (PubChem CID: 5281855) Quercetin-3-O-glucuronide Faculty of Chemistry and Chemical Engineering, “Babeş-Bolyai” University, Cluj-Napoca, Romania.
U 26 cornus mas free#
Many of these biological functions have beenĪttributed to their free radical scavenging capacity and antioxidant activity. Including antibacterial, anti-inflammatory, hepatoprotective,Īnti-allergic, antiviral, antithrombotic, vasodilatatory andĪnticarcinogenic actions (Mizgier et al., 2016 Xie, Huang, Zhang, Polyphenolics exhibit a wide range of biological effects, Phenolics, including flavonoids, are non-nutritive components which contribute to the antioxidant activity of individualįruits.
Reactions (Scalzo, Politi, Pellegrini, Mezzetti, & Battino, 2005). Major role in the protective effect against cellular oxidation Good source of various nutrients and non-nutrients, many of The consumption of fruits and vegetables plays an important role in human health. Matory reaction while high dose inhibited the exudation of inflammatory cells to the The histopathological investigation of pawĪ nd liver samples revealed that low dose of CM extract attenuated the initial acute inflam. In paw tissue, enhancing the production of IL-10. CM extract showed potent in vitro antioxidantĪctivity and also led to significant suppression of interleukin (IL)-1β and IL-13 production Of Wistar rats after inducing inflammation. The anti-inflammatoryĮffect of CM extract was evaluated by analysing the cytokine levels in the soft paw tissue Of CM extract revealed the presence of 10 main phenolic compounds. The high-performance liquid chromatography (HPLC) profile The in vitro antioxidant activity was evalu-Īted by ferric reducing ability of plasma (FRAP) and by the 2,2′-azinobis-3-ethyl-benzthiazino-Ħ-sulphonic acid (ABTS) test. Vitro antioxidant properties was investigated. The biological activity of Cornus mas fruits (CM) on acute inflammation in relation to the in Ramona Suharoschi c, Pompei Bolfa d,e, Luminita David a,*įaculty of Chemistry and Chemical Engineering, “Babeş-Bolyai” University, Cluj-Napoca, Romaniaĭepartment of Physiology, University of Medicine and Pharmacy, Cluj-Napoca, Romaniaįaculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romaniaĭepartment of Pathology, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romaniaĭepartment of Biomedical Sciences, Ross University School of Veterinary Medicine, Basseterre, Saint Kitts and Nevis (Cornus mas L.) fruits extract and the in vivoĮvaluation of its anti-inflammatory effectsīianca Moldovan a, Adriana Filip b, Simona Clichici b, Journal of Functional Foods 26 (2016) 77–87
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